English actor Bob Hoskins has announced retirement from his acting career after he was diagnosed with Parkinson’s disease.

According to reports, 69-year-old Bob Hoskins announcement brings an end to his silver screen career which lasted for four decades and also included Hollywood hits like “Who Framed Roger Rabbit.”

His most recent stint was in “Snow White and the Huntsman,” which was released this year and stars “Twilight” actress Kristen Stewart.

On Tuesday, Bob Hoskins revealed his battle with Parkinson’s disease, several months after he was diagnosed with the brain disorder. His agent released a statement regarding the condition of the actor:

“Bob Hoskins wishes to announce that he will be retiring from acting, following his diagnosis of Parkinson’s disease last autumn. He wishes to thank all the great and brilliant people he has worked with over the years, and all of his fans who have supported him during a wonderful career. Bob is now looking forward to his retirement with his family, and would greatly appreciate that his privacy be respected at this time.”

Some of the symptoms of Parkinson’s disease include difficulty with movement, gradual slowing down of the body, muscle stiffness and tremors. Balance and facial expression can also be affected.

Daiga Heisters of support and research charity Parkinson’s disease UK said: “We are sorry to learn that Bob Hoskins has been diagnosed with Parkinson’s. Parkinson’s is a progressive condition that affects everybody differently, and can change on a daily, or even hourly, basis.”

Heisters added, “Many people can live a full and active life with their diagnosis of Parkinson’s. However, it does affect some people quickly and severely.”

Actor Michael J Fox is one of the most well-known celebrity who also suffers from the brain disorder. He has battled Parkinson’s disease for more than 20 years. The actor was diagnosed at the age of 30

Actor Michael J Fox is one of the most well-known sufferers of the disease, which he has battled for more than 20 years. He was diagnosed at the age of 30, but he chose not to make the news public for another seven years. Michael J Fox is now 51, and his foundation is the biggest contributor of private funding to research into Parkinson’s disease.

Another high-profile celebrity who suffered from the disease is Muhammad Ali, who was diagnosed when he was 42 years old back in 1984. The former champion boxer, who is now 70, has cut an increasingly frail figure in recent years.

Majority of the cases of Parkinson’s disease appear for no known reason, but experts believe that repeated blows to the head may have contributed to the onset of the disease in the case of Muhammad Ali.

Bob Hoskins began his career in film during the 1970s and gained popularity by playing Harold Shand in the iconic 1980 gangster film “The Long Good Friday” alongside Helen Mirren. Back in 1986, an Oscar nomination for Best Actor and further critical acclaim followed his lead role in yet another British film, “Mona Lisa.”

Hoskins also played the role of Eddie Valiant in the movie “Who Framed Roger Rabbit” in 1988, and Smee in both Hook (1991) and Neverland (2011).

Back in the 1980s and 1990s, Bob Hoskins was also famous for his advertisements for BT, and his “It’s good to talk” catchphrase became famous.

The English actor has four children and has lived in East Sussex, England with second wife Linda Banwell for more than ten years. In May, when he was asked if acting was still a passion of his, Bob Hoskins replied: “Acting is a lark but I’m trying to work less. They say: “Bob I know you’re trying to retire but we’ve got a little swan song here which is the business…” and I get talked into it.

Hoskins added, “The more you don’t want to work, the more work you get. I want to be at home with the wife but she doesn’t want me to retire, she wants me out of the house.”